Dog Flea Medicine

Dog flea medicine is the latest tool in the battle against dog flea infestations. These flea medicines are easy to apply and generally provide long lasting relief from fleabites and also protect the dog against further infestations.

Dog flea medicine comes in a variety of delivery methods. Some dog flea medicines are in pill form, some you spray directly onto your dog where it is absorbed through the skin, and some are given to the dog orally through its food or in the form of drops.

While these new dog flea medicines are very effective, they should be used only under the direction of your veterinarian. They can interact negatively with other of your dog’s health problems. But if you check with your vet, he or she can recommend a specific kind of dog flea medicine based on his or her personal experience and the dog’s weight.Dog Flea Medicine

Over The Counter Dog Flea Medicine

K9 Advantix

The first of these is K9 Advantix®, a flea medicine from the Bayer company. K9 Advantix comes in the form of drops and is said to be effective also against ticks and mosquitoes. You apply it to the dog’s skin between its shoulder blades. One study of this product suggested that for ticks it is substantially better than Frontline® but only for killing ticks. One of Advantix’s biggest selling points is that it will get rid of a broader range of insects than just fleas.

K9 Advantix normally sells for $42 to $75 for dogs weighing one to 10 lbs, $$39 to $79 for dogs of 11–20 lbs., $42 to $83 for dogs of 20-55 lbs. and so forth.

Frontline Plus

Like K9 Advantix, this flea medicine is applied in the form of drops, which go directly onto your dog’s skin between its shoulder blades. While applying several drops doesn’t seem like much of a dog flea treatment, it can give your dog effective flea control for an entire month. Drops are often much easier to use with your dog, especially if it’s reluctant to be treated as many dogs become anxious or agitated if you try to spray or bathe them.

Frontline Plus’ manufacturer says that from the very first application, the product will kill up to 100% of existing fleas in less than 24 hours and will continue to provide fast-acting, long-lasting flea and tick control.

Frontline Plus is waterproof and will not rinse off. However, you should still not bathe your dog for a few days after applying it.

Frontline Plus typically is priced at around $43 dogs weighing less than 22 lbs., $34 for dogs weighing 23-44 pounds; and $35to $86 for dogs weighing 45 to 88 lbs., and on up.

ProMeris For Dogs

ProMeris for Dogs is a topical dog flea medicine that controls existing flea and tick infestations, and is said to prevent re-infestation. This product can also used to control chewing lice and Demodectic mange. Promeris for dogs is available in 3, 6, and 12 dose packages. It usually sells for around $42 for dogs up to 22 lbs., $43 for dogs 22 to 55 lbs., $45 for dogs 55-88 lbs., and $46 for dogs 88-110 lbs.

Vectra 3D

This is a relatively new dog flea medicine. It is a topical solution that is applied to the dog’s skin once a month. One of Vectra’s main ingredients, permethrin, is well tolerated by both dogs and people.

Vectra protects against four types of ticks, three types of mosquitoes and all stages of fleas. In fact, according to its manufacture, it will kill 96% of fleas in six hours after application. Vectra is a topical treatment that is easy to apply and remains effective even after bathing or swimming. Most interestingly, the company guarantees it will work or it will refund your purchase price. Vectra is available only from a veterinarian.

Bio Spot Spot-on Flea and Tick Control

This flea medicine has both an insecticide to kill and repel adult fleas and an insect growth regulator. The growth regulator prevents flea eggs and larvae from developing into those nasty adults that bite your dog. The way it works is that it kills the eggs so that their life cycle is broken and they cannot develop into adults.

Bio Spot is a topical solution that is applied to the dog’s skin between its shoulder blades. One tube of Bio Spot (1.5mL) will treat a dog weighing 15 lbs. and under. For dogs that weigh 33 pounds and more, you should apply half of the 3 ml tube between his shoulder blades as a spot or streak and then apply the rest of the tube’s contents to the dogs back as a spot or streak directly in front of the base of the tale.

Bio-Spot comes in an easy-to-apply, spot-on dispenser. It usually costs around $10 for a three pack.

Dog Flea Medicines Only Available Through Your Vet

Advantage Topical Solution

Your dog will be ecstatic with how fast and easy it is to use Advantage Flea Control. This topical dog flea medicine is available only from your vet who will determine the correct dosage for your pet by his/her weight. Once a month, you apply the pre-measured dose to your dog, where it then spreads naturally onto the surface of its skin.

Advantage Topical Solution is applied in four places, from you dog’s shoulder to the base of its tail. The product is available in four different dosages. Your veterinarian will determine which one you should use based on your dog’s weight. It costs around $36 for small dogs, $38 for medium-sized dogs, $39 for large dogs and $41 for giant dogs.

Prescription Dog Flea Medicine

Revolution Flea Treatment

This product, which is sold by Pfizer, is the first flea control medicine that also provides protection against heartworm in dogs.

Its active ingredient is Selemactin, which kills both adult fleas and flea larvae, and also kills ticks. It is active against ear mites, and sarcoptic mange mites.

Revolution comes in a small pack, which is applied, between the dog’s shoulder blades. It is then rapidly absorbed through the dogs skin and enters into the bloodstream. This is why Revolution is also able to kill off intestinal parasites. Revolution is said to kill fleas within 48 hours and its activity can last for up to one month. A 6-pack of Revolution ranges in price from $42 for dogs less than 5 lbs., up to $65 for dogs as large as 130 lbs.Prescription Dog Flea Medicine


This dog flea medicine is said by its manufacturer to be the first FDA-approved, chewable, beef flavored tablet that kills fleas and prevents flea infestations on your dog for a full month. It is a highly effective, once-a-month pill for flea control. The way Comfortis works is that it circulates in your dog’s bloodstream and kills fleas when they bite. Because fleas bite frequently, Comfortis works fast. It is also said that Comfortis will start killing fleas within 30 minutes and that it kills them before they can lay eggs. Plus, it stays completely within the dog.

Comfortis is a convenient solution because you can place the tablet directly into the dog’s mouth or put it in its food. Its price normally ranges from $75 for dogs weighing 10 lbs. or less up to $83 for dogs as large as 120 lbs.


This pill is a monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. However, it will not kill adult fleas.

Sentinel comes in the form of a flavor tab tablet. A six-month supply usually costs from $47 for dogs and puppies 2 to 10 lbs. up to $93 for dogs 51 to 100 lbs.

Program Flea Control

These flavor tabs from Novartis provide an easy way to administer protection to your dog. This product contains lufenuron, an insect growth regulator that breaks the flea lifecycle at its base, preventing flea eggs and larvae from developing. While it is a good insect development inhibitor, Program Flea Control does not kill adult fleas.

It should be given at the same time each month with a meal.

Program Flea Control is usually available at about $38 for dogs up to 10 lbs.; $45 for dogs 11 to 20 lbs.; $27 for dogs weighing 21 to 45 lbs.; and $48 for dogs 45 lbs. and up.

Advantages And Disadvantages Of Dog Flea Medicine

The advantages of these various medications are that they are convenient, easy to apply and will keep your dog flea free for as long as a month.

The major disadvantage of a dog flea medicine is their cost, especially in the case of the prescription flea medicines. And because they are medicines, you really should use them only under a vet’s direction. He or she can counsel you as to the best solution for your dog and will provide advice about dosages based on your dog’s weight and general condition.

There have also been cases where dog flea medicines caused serious problems for dogs because of their interaction with other drugs or because the dog was suffering from some other disease. Consulting with your vet can make sure this doesn’t happen to your dog.

A dog flea medicine is considered to be the most effective way to kill fleas and protect your dog form re-infestation. Of the medicines listed here, those available only through a veterinarian are thought to be the most effective anti-flea solution.

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